WebJul 13, 2024 · This multicenter retrospective matched cohort study evaluated the use of daptomycin and ceftaroline for >72hrs in MRSA bacteremia. Patients were match with those using standard of care based on the source, age + or -10yrs and renal function. End point was all cause 30 day mortality, duration of bacteremia, and relapse/recurrence. WebApr 9, 2024 · For methicillin-resistant Staphylococcus aureus (MRSA) bacteremia and endocarditis, vancomycin represents 1 of the 2 accepted standards of care, along with daptomycin [ 2 ]. However, recent studies indicate that when given the choice between these 2 treatments against MRSA bacteremia, >96% of clinicians choose vancomycin [ …
STANDARD-OF-CARE (SOC) FOR MRSA BACTEREMIA: ROOM FOR …
WebJun 24, 2024 · Daptomycin. Drugs appearing to distribute into total body water (Vd 0.7-1 L/kg) Clindamycin. Doxycycline. Linezolid. Metronidazole. Rifampin. Vancomycin. Drugs that enter the tissues (Vd >1 L/kg) Ceftaroline (20 L/kg). Macrolides: Azithromycin (30 L/kg). Clarithromycin (3 L/kg). Tigecycline (8 L/kg). Trimethoprim (2 L/kg). augmented renal … WebNov 25, 2024 · Purpose: Staphylococcus aureus is a leading cause of bacteremia with a 30-day mortality of 20%. This study evaluated outcomes after implementation of a pharmacist-driven Staphylococcus aureus bacteremia (SAB) initiative in a community hospital. Methods: This retrospective cohort analysis compared patients admitted with … onslow road salcombe
Methicillin-resistant Staphylococcus aureus bacteremia among …
WebMar 19, 2024 · In that study, it was found that daptomycin vs standard of care yielded a 12.6% difference in treatment success (95% confidence interval, –7.4% to 32.6%), favoring daptomycin for MRSA; however, this was confounded by addition of gentamicin to the standard care group. WebThis is the first matched study comparing early daptomycin versus vancomycin for the treatment of MRSAB when the vancomycin MIC is >1 µg/mL. Treatment with daptomycin resulted in significantly improved outcomes, including decreased 30-day mortality and persistent bacteremia. These results support … WebApr 2, 2024 · Vancomycin (VCM) and daptomycin (DAP) are standard therapies for methicillin-resistant Staphylococcus aureus (MRSA) bacteremia, despite concerns … onslow road shenton park bakery