WebCircular RNAs (circRNAs) are characteristic of unique covalently closed loops and constitute a new family of endogenous noncoding RNAs (ncRNAs). ... Nevertheless, a comprehensive understanding of the expression and function of circRNAs in unstable plaques is lacking. This study identified DE circRNAs between unstable and stable … WebMay 19, 2024 · (a) microRNA sponge function: circRNAs can act as microRNA sponges and suppress the effects of microRNAs on target mRNAs; (b) protein sponge function: circRNAs with RBP binding sites can act as protein sponges and inhibit normal functions of associated proteins; (c) protein scaffold function: circRNAs can act as protein …
Circular RNAs in body fluids as cancer biomarkers: the new …
WebAug 3, 2024 · Together, available data suggest that circRNAs have important roles in synaptic plasticity and neuronal function. This review covers current advances in the field and lays out hypotheses regarding functions of circRNAs in the brain as well as their putative involvement in initiation and progression of neurodegenerative processes. WebNov 28, 2024 · Another important function of circRNAs is the regulation of parental gene expression. First, circRNAs can directly interact with host genes. ... It is believed that with the unremitting efforts and practical exploration of scientists, circRNAs will open up a new field for tumor research, hopefully creating a new starting point for precision ... tapping with yates grits
The new function of circRNA: translation - PubMed
WebThe identification of the potential functions of circRNAs provides a foundation for understanding the genetic mechanisms that regulate oocyte growth and maturation, which will allow the efficiency of tongue sole reproduction to be improved. Moreover, our findings extend the knowledge about a new type of endogenous RNA involved in regulating the ... WebAug 15, 2024 · Recent reports also demonstrate functions for some circRNAs in trans: Certain circRNAs interact with microRNAs, some are translated, and circRNAs have been shown to regulate immune responses and behavior. ... Here, we review current knowledge about animal circRNAs and summarize new insights into potential circRNA functions, … WebMar 6, 2024 · Furthermore, looking for circRNAs with high specificity and sensitivity will provide a new opportunity for the early diagnosis, clinical treatment, and prognosis monitoring of TNBC. Herein, we reviewed the biogenesis, regulatory mechanisms, and biological functions of circRNAs in TNBC and summarized the relationship between … tapping word sounds